Association of IL18 genetic polymorphisms with Chagas disease in Latin American populations.

• Main Authors: Mariana Strauss (Author), Marialbert Acosta-Herrera (Author), Alexia Alcaraz (Author), Desiré Casares-Marfil (Author), Pau Bosch-Nicolau (Author), María Silvina Lo Presti (Author), Israel Molina (Author), Clara Isabel González (Author), Chagas Genetics CYTED Network (Author), Javier Martín (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Host genetic factors have been suggested to play an important role in the susceptibility to Chagas disease. Given the influence of interleukin 18 (IL-18) in the development of the disease, in the present study, we analyzed three IL18 genetic variants (rs2043055, rs1946518, rs360719) regarding the pr...