Asiaticoside improves depressive-like behavior in mice with chronic unpredictable mild stress through modulation of the gut microbiota

• Main Authors: Qingyi Ren (Author), Chenxi He (Author), Yuhong Sun (Author), Xiaowei Gao (Author), Yan Zhou (Author), Tao Qin (Author), Zhuo Zhang (Author), Xiaodong Wang (Author), Jun Wang (Author), Siping Wei (Author), Fang Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundAsiaticoside, the main active ingredient of Centella asiatica, is a pentacyclic triterpenoid compound. Previous studies have suggested that asiaticoside possesses neuroprotective and anti-depressive properties, however, the mechanism of its anti-depressant action not fully understood. In r...