Lingguizhugan decoction attenuates doxorubicin-induced heart failure in rats by improving TT-SR microstructural remodeling

• Main Authors: Xueping Li (Author), Guangmin Xu (Author), Shujun Wei (Author), Baocheng Zhang (Author), Huan Yao (Author), Yuchi Chen (Author), Weiwei Liu (Author), Baojia Wang (Author), Juan Zhao (Author), Yongxiang Gao (Author)
• Format: Book
• Published: BMC, 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Lingguizhugan decoction (LGZG), an ancient Chinese herbal formula, has been used to treat cardiovascular diseases in eastern Asia. We investigated whether LGZG has protective activity and the mechanism underlying its effect in an animal model of heart failure (HF). Methods A rat...