Use of weight-for-age-data to optimize tablet strength and dosing regimens for a new fixed-dose artesunate-amodiaquine combination for treating falciparum malaria

• Main Authors: Walter RJ Taylor (Author), Dianne J Terlouw (Author), Piero L Olliaro (Author), Nicholas J White (Author), Philippe Brasseur (Author), Feiko O ter Kuile (Author)
• Format: Book
• Published: The World Health Organization.
• Subjects: article
• Online Access: Connect to this object online.

OBJECTIVE: To test a novel methodology to define age-based dosing regimens for the treatment of malaria with a new, user-friendly, blister-packaged fixed-dose combination of artesunate and amodiaquine. METHODS: A weight-for-age reference database of 88 054 individuals from sub-Saharan Africa was com...