Interaction of PICK1 with C-Terminus of Growth Hormone-Releasing Hormone Receptor (GHRHR) Modulates Trafficking and Signal Transduction of Human GHRHR

• Main Authors: Yuriko Katsushima (Author), Takeya Sato (Author), Chika Yamada (Author), Moe Ito (Author), Yuki Suzuki (Author), Eishin Ogawa (Author), Izumi Sukegawa (Author), Jun Sukegawa (Author), Kohji Fukunaga (Author), Teruyuki Yanagisawa (Author)
• Format: Book
• Published: Elsevier, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Release of growth hormone (GH) from the somatotroph is regulated by binding GH-releasing hormone (GHRH) to its cognate receptor (GHRHR), one of the members of the G protein-coupled receptor (GPCR) superfamily. Proteins bound to the carboxy (C)-terminus of GPCR have been reported to regulate intracel...