Active Phagocytosis and Diachronic Processing of Calcium Oxalate Monohydrate Crystals in an in vitro Macrophage Model

• Main Authors: Atsushi Okada (Author), Hiromasa Aoki (Author), Daichi Onozato (Author), Taiki Kato (Author), Tadahiro Hashita (Author), Hiroshi Takase (Author), Teruaki Sugino (Author), Rei Unno (Author), Kazumi Taguchi (Author), Shuzo Hamamoto (Author), Ryosuke Ando (Author), Kentaro Mizuno (Author), Keiichi Tozawa (Author), Tamihide Matsunaga (Author), Kenjiro Kohri (Author), Takahiro Yasui (Author)
• Format: Book
• Published: Karger Publishers, 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: We previously discovered that renal macrophages (Mφs) phagocytose renal calcium oxalate monohydrate (COM) crystals. This study investigated the processing of engulfed crystals using in vitro models. Methods: J774.1 mouse Mφs were exposed to COM crystals and observed for 24 h using polari...