Sophocarpine Suppresses NF-κB-Mediated Inflammation Both In Vitro and In Vivo and Inhibits Diabetic Cardiomyopathy

• Autori principali: Fang Zou (Autore), Ling Wang (Autore), Han Liu (Autore), Wei Wang (Autore), Longlong Hu (Autore), Xiaoying Xiong (Autore), Lijuan Wu (Autore), Yunfeng Shen (Autore), Renqiang Yang (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2019-10-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Diabetic cardiomyopathy (DCM) is a leading cause of mortality in patients with diabetes. DCM is a leading cause of mortality in patients with diabetes. We used both in vitro and in vivo experiments to investigate the hypothesis that sophocarpine (SPC), a natural quinolizidine alkaloid derived from a...