Bilobalide Exerts Anti-Inflammatory Effects on Chondrocytes Through the AMPK/SIRT1/mTOR Pathway to Attenuate ACLT-Induced Post-Traumatic Osteoarthritis in Rats

• Main Authors: Tianwen Ma (Author), Liangyu Lv (Author), Yue Yu (Author), Lina Jia (Author), Xiaopeng Song (Author), XinYu Xu (Author), Ting Li (Author), Xuanbo Sheng (Author), Haoran Wang (Author), Jiantao Zhang (Author), Li Gao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Although osteoarthritis (OA) significantly affects the quality of life of the elderly, there is still no effective treatment strategy. The standardized Ginkgo biloba L. extract preparation has been shown to have a wide range of therapeutic effects. Bilobalide, a unique ingredient of Ginkgo biloba, h...