MiR-132 controls pancreatic beta cell proliferation and survival through Pten/Akt/Foxo3 signaling

• Main Authors: Hassan Mziaut (Author), Georg Henniger (Author), Katharina Ganss (Author), Sebastian Hempel (Author), Steffen Wolk (Author), Johanna McChord (Author), Kamal Chowdhury (Author), Philippe Ravassard (Author), Klaus-Peter Knoch (Author), Christian Krautz (Author), Jürgen Weitz (Author), Robert Grützmann (Author), Christian Pilarsky (Author), Michele Solimena (Author), Stephan Kersting (Author)
• Format: Book
• Published: Elsevier, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: MicroRNAs (miRNAs) play an integral role in maintaining beta cell function and identity. Deciphering their targets and precise role, however, remains challenging. In this study, we aimed to identify miRNAs and their downstream targets involved in the regeneration of islet beta cells follo...