Monoclonal Antibodies for Systemic Lupus Erythematosus (SLE)

• المؤلفون الرئيسيون: Gabriella Moroni (مؤلف), Claudio Ponticelli (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2010-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

A number of monoclonal antibodies (mAb) are now under investigation in clinical trials to assess their potential role in Systemic Lupus Erythematosus (SLE). The most frequently used mAb is rituximab, which is directed against CD20, a membrane protein expressed on B lymphocytes. Uncontrolled trials r...