IRAK-M regulation and function in host defense and immune homeostasis

• Principais autores: Leah L.N. Hubbard (Autor), Bethany B. Moore (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2010-06-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Antigen presenting cells (APCs) of the innate immune system sense a wide range of pathogens via pattern recognition receptors (PRRs). Engagement of certain PRRs can induce production of pro-inflammatory mediators that facilitate effective clearance of pathogen. Toll-like receptors (TLRs) are a well...