Peran p53 Sebagai Jalur Kritis pada Mekanisme Kontrol Siklus Sel Sebagai Pencegah Terjadinya Kanker Mulut

• Main Authors: Herlia Nur Istindiah (Author), Elza Ibrahim Auerkari (Author)
• Format: Knjiga
• Izdano: Faculty of Dentistry, Universitas Indonesia, 2015-09-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

<p>In cell cycle control, p53 acts as an emergency brake, where its important checkpoint function is to maintain the genome integrity by preventing the formation and proliferation of mutant cells. P53 activity is increased by DNA damage occurs caused by agents (such as radioation, UV light or...