Complete Protection against Pneumonic and Bubonic Plague after a Single Oral Vaccination.

• Main Authors: Anne Derbise (Author), Yuri Hanada (Author), Manal Khalifé (Author), Elisabeth Carniel (Author), Christian E Demeure (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:No efficient vaccine against plague is currently available. We previously showed that a genetically attenuated Yersinia pseudotuberculosis producing the Yersinia pestis F1 antigen was an efficient live oral vaccine against pneumonic plague. This candidate vaccine however failed to confer...