iTRAQ-derived quantitative proteomics uncovers the neuroprotective property of bexarotene in a mice model of cerebral ischemia-reperfusion injury

• Autores principales: Hailin Liu (Autor), Hu Wang (Autor), Sisi Chen (Autor), Shengwei Liu (Autor), Xiaocui Tian (Autor), Zhi Dong (Autor), Lu Xu (Autor)
• Formato: Libro
• Publicado: Elsevier, 2022-05-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Bexarotene, a FDA-approved drug for cutaneous lymphoma, has been shown to exert brain protective effects. In previous study, we demonstrated that Bexarotene protects against cerebral ischemic stroke by suppressing the JNK/Caspase-3 signaling pathway. However, the molecular mechanisms by which Bexaro...