Schistosoma mansoni-mediated suppression of allergic airway inflammation requires patency and Foxp3+ Treg cells.

• Main Authors: Laura E Layland (Author), Kathrin Straubinger (Author), Manuel Ritter (Author), Eva Loffredo-Verde (Author), Holger Garn (Author), Tim Sparwasser (Author), Clarissa Prazeres da Costa (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The continual rise of asthma in industrialised countries stands in strong contrast to the situation in developing lands. According to the modified Hygiene Hypothesis, helminths play a major role in suppressing bystander immune responses to allergens, and both epidemiological and experimental studies...