Three to Tango: Inhibitory Effect of Quercetin and Apigenin on Acetylcholinesterase, Amyloid-β Aggregation and Acetylcholinesterase-Amyloid Interaction

• Main Authors: Irene Álvarez-Berbel (Author), Alba Espargaró (Author), Antonio Viayna (Author), Ana Belén Caballero (Author), Maria Antònia Busquets (Author), Patrick Gámez (Author), Francisco Javier Luque (Author), Raimon Sabaté (Author)
• Format: Book
• Published: MDPI AG, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

One of the pathological hallmarks of Alzheimer's disease (AD) is the formation of amyloid-β plaques. Since acetylcholinesterase (AChE) promotes the formation of such plaques, the inhibition of this enzyme could slow down the progression of amyloid-β aggregation, hence being complementary to the...