Cancer Stem Cell Quiescence and Plasticity as Major Challenges in Cancer Therapy

• Main Authors: Wanyin Chen (Author), Jihu Dong (Author), Jacques Haiech (Author), Marie-Claude Kilhoffer (Author), Maria Zeniou (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cells with stem-like properties, tumorigenic potential, and treatment-resistant phenotypes have been identified in many human malignancies. Based on the properties they share with nonneoplastic stem cells or their ability to initiate and propagate tumors in vivo, such cells were designated as cancer...