Celastrol alleviates diabetic vascular injury via Keap1/Nrf2-mediated anti-inflammation

• Main Authors: Ning An (Author), Rixiang Wang (Author), Lin Li (Author), Bingyu Wang (Author), Huiting Wang (Author), Ganyu Peng (Author), Hua Zhou (Author), Gen Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Celastrol (Cel) is a widely used main component of Chinese herbal medicine with strong anti-inflammatory, antiviral and antitumor activities. In the present study, we aimed to elucidate the cellular molecular protective mechanism of Cel against diabetes-induced inflammation and endothe...