Celastrol alleviates diabetic vascular injury via Keap1/Nrf2-mediated anti-inflammation

• Egile Nagusiak: Ning An (Egilea), Rixiang Wang (Egilea), Lin Li (Egilea), Bingyu Wang (Egilea), Huiting Wang (Egilea), Ganyu Peng (Egilea), Hua Zhou (Egilea), Gen Chen (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2024-05-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Introduction: Celastrol (Cel) is a widely used main component of Chinese herbal medicine with strong anti-inflammatory, antiviral and antitumor activities. In the present study, we aimed to elucidate the cellular molecular protective mechanism of Cel against diabetes-induced inflammation and endothe...