The Effect of Triptolide Combined With Crocin on Arthritis in Mice: From Side Effect Attenuation to Therapy

• Päätekijät: Min Yan (Tekijä), Yinyin Yan (Tekijä), Zhenqiang Zhang (Tekijä), Guoqiang Wang (Tekijä), Wenbo Shi (Tekijä), Mengyuan Jiang (Tekijä), Junwei Zhao (Tekijä), Xiangxiang Wu (Tekijä), Huahui Zeng (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Clinical use of triptolide (TP) is restricted due to severe toxicity. This study assessed the protective effect of crocin (CR) as a natural antioxidant against TP-induced toxicity in bovine collagen type II-induced arthritis (CIA) in mice. The mice in the CIA model group showed macroscopic signs of...