Dengue virus activates membrane TRAIL relocalization and IFN-α production by human plasmacytoid dendritic cells in vitro and in vivo.

• Главные авторы: Mariana Gandini (Автор), Christophe Gras (Автор), Elzinandes Leal Azeredo (Автор), Luzia Maria de Oliveira Pinto (Автор), Nikaïa Smith (Автор), Philippe Despres (Автор), Rivaldo Venâncio da Cunha (Автор), Luiz José de Souza (Автор), Claire Fernandes Kubelka (Автор), Jean-Philippe Herbeuval (Автор)
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• Опубликовано: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Предметы: article
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BACKGROUND: Dengue displays a broad spectrum of clinical manifestations that may vary from asymptomatic to severe and even fatal features. Plasma leakage/hemorrhages can be caused by a cytokine storm induced by monocytes and dendritic cells during dengue virus (DENV) replication. Plasmacytoid dendri...