Dengue virus activates membrane TRAIL relocalization and IFN-α production by human plasmacytoid dendritic cells in vitro and in vivo.

• मुख्य लेखकों: Mariana Gandini (लेखक), Christophe Gras (लेखक), Elzinandes Leal Azeredo (लेखक), Luzia Maria de Oliveira Pinto (लेखक), Nikaïa Smith (लेखक), Philippe Despres (लेखक), Rivaldo Venâncio da Cunha (लेखक), Luiz José de Souza (लेखक), Claire Fernandes Kubelka (लेखक), Jean-Philippe Herbeuval (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

BACKGROUND: Dengue displays a broad spectrum of clinical manifestations that may vary from asymptomatic to severe and even fatal features. Plasma leakage/hemorrhages can be caused by a cytokine storm induced by monocytes and dendritic cells during dengue virus (DENV) replication. Plasmacytoid dendri...