Preparation and Characterization of Ion-Sensitive Brimonidine Tartrate In Situ Gel for Ocular Delivery

• Главные авторы: Haonan Xu (Автор), Ye Liu (Автор), Lu Jin (Автор), Xu Chen (Автор), Xinghao Chen (Автор), Qiao Wang (Автор), Zhan Tang (Автор)
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• Опубликовано: MDPI AG, 2023-01-01T00:00:00Z.
• Предметы: article
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Brimonidine tartrate (BRT) is a highly selective α2 adrenergic receptor agonist as treatment for patients with open angle glaucoma and high intraocular pressure. The objective of this study was to formulate an ophthalmic ion-sensitive in situ gel (ISG) of BRT to increase the retention time of the dr...