The macrophage microtubule network acts as a key cellular controller of the intracellular fate of Leishmania infantum.

• Autores principales: Sandrine Cojean (Autor), Valérie Nicolas (Autor), Vanessa Lievin-Le Moal (Autor)
• Formato: Libro
• Publicado: Public Library of Science (PLoS), 2020-07-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

The parasitophorous vacuoles (PVs) that insulate Leishmania spp. in host macrophages are vacuolar compartments wherein promastigote forms differentiate into amastigote that are the replicative form of the parasite and are also more resistant to host responses. We revisited the biogenesis of tight-fi...