Over 40 Years of Fosmidomycin Drug Research: A Comprehensive Review and Future Opportunities

• Main Authors: Talea Knak (Author), Mona A. Abdullaziz (Author), Stefan Höfmann (Author), Leandro A. Alves Avelar (Author), Saskia Klein (Author), Matthew Martin (Author), Markus Fischer (Author), Nobutada Tanaka (Author), Thomas Kurz (Author)
• Format: Book
• Published: MDPI AG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

To address the continued rise of multi-drug-resistant microorganisms, the development of novel drugs with new modes of action is urgently required. While humans biosynthesize the essential isoprenoid precursors isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) via the established m...