Differential Induction of Reactive Oxygen Species and Expression of Antioxidant Enzymes in Human Melanocytes Correlate with Melanin Content: Implications on the Response to Solar UV and Melanoma Susceptibility

• Päätekijät: Parth R. Upadhyay (Tekijä), Renny J. Starner (Tekijä), Viki B. Swope (Tekijä), Kazumasa Wakamatsu (Tekijä), Shosuke Ito (Tekijä), Zalfa A. Abdel-Malek (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2022-06-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Constitutive pigmentation determines the response to sun exposure and the risk for melanoma, an oxidative stress-driven tumor. Using primary cultures of human melanocytes, we compared the effects of constitutive pigmentation on their antioxidant response to solar UV. The quantitation of eumelanin an...