Applications of High-Throughput Sequencing for In Vitro Selection and Characterization of Aptamers

Aptamers are identified through an iterative process of evolutionary selection starting from a random pool containing billions of sequences. Simultaneously to the amplification of high-affinity candidates, the diversity in the pool is exponentially reduced after several rounds of in vitro selection....

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Bibliographic Details
Main Authors: Nam Nguyen Quang (Author), Gérald Perret (Author), Frédéric Ducongé (Author)
Format: Book
Published: MDPI AG, 2016-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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