Berberine Regulates Treg/Th17 Balance to Treat Ulcerative Colitis Through Modulating the Gut Microbiota in the Colon

• Main Authors: Huantian Cui (Author), Yuzi Cai (Author), Li Wang (Author), Beitian Jia (Author), Junchen Li (Author), Shuwu Zhao (Author), Xiaoqian Chu (Author), Jin Lin (Author), Xiaoyu Zhang (Author), Yuhong Bian (Author), Pengwei Zhuang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Berberine (BBR), an alkaloid isolated from Rhizoma Coptidis, Cortex Phellode, and Berberis, has been widely used in the treatment of ulcerative colitis (UC). However, the mechanism of BBR on UC is unknown. In this study, we investigated the activities of T regulatory cell (Treg) and T helper 17 cell...