PEG-Bottlebrush Stabilizer-Based Worm-like Nanocrystal Micelles with Long-Circulating and Controlled Release for Delivery of a BCR-ABL Inhibitor against Chronic Myeloid Leukemia (CML)

• Glavni autori: Huamin Liang (Autor), Fengming Zou (Autor), Liyi Fu (Autor), Qingwang Liu (Autor), Beilei Wang (Autor), Xiaofei Liang (Autor), Jing Liu (Autor), Qingsong Liu (Autor)
• Format: Knjiga
• Izdano: MDPI AG, 2022-08-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Drug nanocrystals, one of most common drug delivery systems, enable the delivery of poorly water-soluble drugs with high drug loading and enhanced dissolution. The rapid clearance and uncontrolled drug release of drug nanocrystals limit their delivery efficiency and clinical application. Herein, an...