PEG-Bottlebrush Stabilizer-Based Worm-like Nanocrystal Micelles with Long-Circulating and Controlled Release for Delivery of a BCR-ABL Inhibitor against Chronic Myeloid Leukemia (CML)

• Autori principali: Huamin Liang (Autore), Fengming Zou (Autore), Liyi Fu (Autore), Qingwang Liu (Autore), Beilei Wang (Autore), Xiaofei Liang (Autore), Jing Liu (Autore), Qingsong Liu (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2022-08-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Drug nanocrystals, one of most common drug delivery systems, enable the delivery of poorly water-soluble drugs with high drug loading and enhanced dissolution. The rapid clearance and uncontrolled drug release of drug nanocrystals limit their delivery efficiency and clinical application. Herein, an...