PEG-Bottlebrush Stabilizer-Based Worm-like Nanocrystal Micelles with Long-Circulating and Controlled Release for Delivery of a BCR-ABL Inhibitor against Chronic Myeloid Leukemia (CML)

• Auteurs principaux: Huamin Liang (Auteur), Fengming Zou (Auteur), Liyi Fu (Auteur), Qingwang Liu (Auteur), Beilei Wang (Auteur), Xiaofei Liang (Auteur), Jing Liu (Auteur), Qingsong Liu (Auteur)
• Format: Livre
• Publié: MDPI AG, 2022-08-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Drug nanocrystals, one of most common drug delivery systems, enable the delivery of poorly water-soluble drugs with high drug loading and enhanced dissolution. The rapid clearance and uncontrolled drug release of drug nanocrystals limit their delivery efficiency and clinical application. Herein, an...