Age‐related decline of interferon‐gamma responses in macrophage impairs satellite cell proliferation and regeneration

• Main Authors: Congcong Zhang (Author), Naixuan Cheng (Author), Bokang Qiao (Author), Fan Zhang (Author), Jian Wu (Author), Chang Liu (Author), Yulin Li (Author), Jie Du (Author)
• Format: Book
• Published: Wiley, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background Impaired muscle regeneration and increased muscle fibrosis are observed in aged muscle accompanied by progressive loss of muscle mass (sarcopenia). However, the underlying mechanism is still unclear. Methods The differentiated expressed genes in young and aged muscles after acute injury b...