Mucin 4 Gene Silencing Reduces Oxidative Stress and Calcium Oxalate Crystal Formation in Renal Tubular Epithelial Cells Through the Extracellular Signal-Regulated Kinase Signaling Pathway in Nephrolithiasis Rat Model

• Main Authors: Ling Sun (Author), Lu-Xi Zou (Author), Jie Wang (Author), Ting Chen (Author), Yu-Chen Han (Author), Dong-Dong Zhu (Author), Shi-Chao Zhuo (Author)
• Format: Book
• Published: Karger Publishers, 2018-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/Aims: Nephrolithiasis plagues a great number of patients all over the world. Increasing evidence shows that the extracellular signal-regulated kinase (ERK) signaling pathway and renal tubular epithelial cell (RTEC) dysfunction and attrition are central to the pathogenesis of kidney diseas...