Chlorambucil Conjugated Ugi Dendrimers with PAMAM-NH<sub>2</sub> Core and Evaluation of Their Anticancer Activity
Herein, a new Ugi multicomponent reaction strategy is described to enhance activity and solubility of the chemotherapeutic drug chlorambucil through its conjugation to poly(amidoamine) (PAMAM-NH<sub>2</sub>) dendrimers with the simultaneous introduction of lipidic (<i>i</i>-P...
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Main Authors: | , , , , |
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Format: | Book |
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MDPI AG,
2019-02-01T00:00:00Z.
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A1234.567 |
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Copy 1 | Available |