Pharmacokinetic Study and Metabolite Identification of 1-(3'-bromophenyl)-heliamine in Rats

• Main Authors: Ruqi Xi (Author), Rahima Abdulla (Author), Miaomiao Zhang (Author), Zhurakulov Sherzod (Author), Vinogradova Valentina Ivanovna (Author), Maidina Habasi (Author), Yongqiang Liu (Author)
• Formato: Libro
• Publicado: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Tetrahydroisoquinolines have been widely investigated for the treatment of arrhythmias. 1−(3'−bromophenyl)−heliamine (BH), an anti−arrhythmias agent, is a synthetic tetrahydroisoquinoline. This study focuses on the pharmacokinetic characterization of BH, as well as the identification of its met...