SorLA in astrocytes regulates blood-brain barrier integrity

• Main Authors: Andrea E. Toth (Author), Adrian Klepe (Author), Dora V. Lipka (Author), Charlotte Goldeman (Author), Birger Brodin (Author), Morten S. Nielsen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The brain`s homeostasis depends heavily on the integrity of the blood-brain barrier (BBB). Astrocytes are an essential part of the BBB in modulating and maintaining the barrier properties of the brain endothelial cells (BECs). Despite decades of research, the elements of glial regulation are not ful...