A single dose recombinant AAV based CHIKV vaccine elicits robust and durable protective antibody responses in mice.

• Main Authors: Qin-Xuan Zhu (Author), Ya-Nan Zhang (Author), Hong-Qing Zhang (Author), Chao Leng (Author), Cheng-Lin Deng (Author), Xin Wang (Author), Jia-Jia Li (Author), Xiang-Li Ye (Author), Bo Zhang (Author), Xiao-Dan Li (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Chikungunya virus (CHIKV) is a mosquito-borne alphavirus that is responsible for Chikungunya fever, which is characterized by fever, rash, and debilitating polyarthralgia. Since its re-emergence in 2004, CHIKV has continued to spread to new regions and become a severe...