Real-Life Vancomycin Therapeutic Drug Monitoring in Coagulase-Negative Staphylococcal Bacteremia in Neonatal and Pediatric Intensive Care Unit: Are We Underestimating Augmented Renal Clearance?

• Main Authors: Claudia Sette (Author), Marcello Mariani (Author), Luca Grasselli (Author), Alessio Mesini (Author), Carolina Saffioti (Author), Chiara Russo (Author), Roberto Bandettini (Author), Andrea Moscatelli (Author), Luca A. Ramenghi (Author), Elio Castagnola (Author)
• Format: Book
• Published: MDPI AG, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bloodstream infections (BSI) from coagulase-negative-staphylococci (CoNS) are among the most frequent healthcare-related infections. Their treatment involves the use of vancomycin, a molecule whose optimal pharmacokinetic/pharmacodynamic (PK/PD) target for efficacy and safety is an area-under-curve/...