The reprotoxic adverse side effects of neurogenic and neuroprotective drugs: current use of human organoid modeling as a potential alternative to preclinical models

• Main Authors: Mariam M. Abady (Author), Ji-Seon Jeong (Author), Ha-Jeong Kwon (Author), Abdullah M. Assiri (Author), Jongki Cho (Author), Islam M. Saadeldin (Author)
• Format: Bog
• Udgivet: Frontiers Media S.A., 2024-06-01T00:00:00Z.
• Fag: article
• Online adgang: Connect to this object online.

The management of neurological disorders heavily relies on neurotherapeutic drugs, but notable concerns exist regarding their possible negative effects on reproductive health. Traditional preclinical models often fail to accurately predict reprotoxicity, highlighting the need for more physiologicall...