Scleral remodeling during myopia development in mice eyes: a potential role of thrombospondin-1

• Main Authors: Junhan Chen (Author), Shin-ichi Ikeda (Author), Yajing Yang (Author), Yan Zhang (Author), Ziyan Ma (Author), Yifan Liang (Author), Kazuno Negishi (Author), Kazuo Tsubota (Author), Toshihide Kurihara (Author)
• Format: Book
• Published: BMC, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Scleral extracellular matrix (ECM) remodeling plays a crucial role in the development of myopia, particularly in ocular axial elongation. Thrombospondin-1 (THBS1), also known as TSP-1, is a significant cellular protein involved in matrix remodeling in various tissues. However, th...