Purification and Biochemical Characterization of Taxadiene Synthase from <i>Bacillus koreensis</i> and <i>Stenotrophomonas maltophilia</i>

• मुख्य लेखकों: Ashraf S. A. El-Sayed (लेखक), Maher Fathalla (लेखक), Ahmed A. Shindia (लेखक), Amgad M. Rady (लेखक), Ashraf F. El-Baz (लेखक), Yara Morsy (लेखक), Basel Sitohy (लेखक), Mahmoud Sitohy (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2021-11-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Taxadiene synthase (TDS) is the rate-limiting enzyme of Taxol biosynthesis that cyclizes the geranylgeranyl pyrophosphate into taxadiene. Attenuating Taxol productivity by fungi is the main challenge impeding its industrial application; it is possible that silencing the expression of TDS is the most...