Purification and Biochemical Characterization of Taxadiene Synthase from <i>Bacillus koreensis</i> and <i>Stenotrophomonas maltophilia</i>

• Κύριοι συγγραφείς: Ashraf S. A. El-Sayed (Συγγραφέας), Maher Fathalla (Συγγραφέας), Ahmed A. Shindia (Συγγραφέας), Amgad M. Rady (Συγγραφέας), Ashraf F. El-Baz (Συγγραφέας), Yara Morsy (Συγγραφέας), Basel Sitohy (Συγγραφέας), Mahmoud Sitohy (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: MDPI AG, 2021-11-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Taxadiene synthase (TDS) is the rate-limiting enzyme of Taxol biosynthesis that cyclizes the geranylgeranyl pyrophosphate into taxadiene. Attenuating Taxol productivity by fungi is the main challenge impeding its industrial application; it is possible that silencing the expression of TDS is the most...