Elevated expression of the V-ATPase C subunit triggers JNK-dependent cell invasion and overgrowth in a Drosophila epithelium

SUMMARY The C subunit of the vacuolar H+-ATPase or V-ATPase regulates the activity and assembly of the proton pump at cellular membranes. It has been shown to be strongly upregulated in oral squamous cell carcinoma, a highly metastatic epithelial cancer. In addition, increased V-ATPase activity appe...

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Main Authors: Astrid G. Petzoldt (Author), Eva Maria Gleixner (Author), Arianna Fumagalli (Author), Thomas Vaccari (Author), Matias Simons (Author)
Format: Book
Published: The Company of Biologists, 2013-05-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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