The types of hepatic myofibroblasts contributing to liver fibrosis of different etiologies.

• Main Authors: Jun eXu (Author), Xiao eLiu (Author), Yukinori eKoyama (Author), Ping eWang (Author), Tian eLan (Author), In-Gyu eKim (Author), In Hee eKim (Author), Hsiao-Yen eMa (Author), Tatiana eKisseleva (Author)
• Format: Book
• Published: Frontiers Media S.A., 2014-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Liver fibrosis results from dysregulation of normal wound healing, inflammation, activation of myofibroblasts and deposition of extracellular matrix (ECM). Chronic liver injury causes death of hepatocytes and formation of apoptotic bodies, which in turn, release factors that recruit inflammatory cel...