Design and Synthesis of Novel Bis-Imidazolyl Phenyl Butadiyne Derivatives as HCV NS5A Inhibitors

• Main Authors: Jehad Hamdy (Author), Nouran Emadeldin (Author), Mostafa M. Hamed (Author), Efseveia Frakolaki (Author), Sotirios Katsamakas (Author), Niki Vassilaki (Author), Grigoris Zoidis (Author), Anna K. H. Hirsch (Author), Mohammad Abdel-Halim (Author), Ashraf H. Abadi (Author)
• Format: Book
• Published: MDPI AG, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In today's global plan to completely eradicate hepatitis C virus (HCV), the essential list of medications used for HCV treatment are direct-acting antivirals (DAAs), as interferon-sparing regimens have become the standard-of-care (SOC) treatment. HCV nonstructural protein 5A (NS5A) inhibitors a...