α1-adrenoceptor ligands inhibit chemokine receptor heteromerization partners of α1B/D-adrenoceptors via interference with heteromer formation

We reported previously that α1-adrenoceptor (α1-AR) ligands inhibit chemokine receptor (CR) heteromerization partners of α1B/D-AR. The underlying mechanisms are unknown and in vivo evidence for such effects is missing. Utilizing CCR2 and α1B-AR as prototypical partners, we observed in recombinant sy...

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Príomhchruthaitheoirí: Xianlong Gao (Údar), Garrett A. Enten (Údar), Michelle Y. McGee (Údar), McWayne Weche (Údar), Matthias Majetschak (Údar)
Formáid: LEABHAR
Foilsithe / Cruthaithe: Elsevier, 2023-04-01T00:00:00Z.
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