Pharmacokinetic and Pharmacodynamic Characteristics of Pelubiprofen Tromethamine vs. Pelubiprofen in Healthy Subjects

• Main Authors: Yu-Jeong Son (Author), Min-Kyu Park (Author), Hyeon-Jeong Park (Author), Ha-Yeon Kim (Author), Ye-Lim Jang (Author), Young-Sim Choi (Author), Jun-Gi Hwang (Author), Ji-Hyung Seo (Author), Yu-Kyong Kim (Author)
• Format: Book
• Published: MDPI AG, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Compared to pelubiprofen, a cyclooxygenase-2-selective inhibitor, pelubiprofen tromethamine has been reported to exhibit improved solubility and absorption. Pelubiprofen tromethamine combines the anti-inflammatory effect of pelubiprofen with the gastric protective function of tromethamine salt, maki...