USP5 Sustains the Proliferation of Glioblastoma Through Stabilization of CyclinD1

• Main Authors: Gen Li (Author), Tianquan Yang (Author), Yanling Chen (Author), Jianping Bao (Author), Di Wu (Author), Xiaohan Hu (Author), Chenxi Feng (Author), Lixiao Xu (Author), Mei Li (Author), Gang Li (Author), Meifang Jin (Author), Yunyun Xu (Author), Rui Zhang (Author), Guanghui Qian (Author), Jian Pan (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Glioblastoma multiforme (GBM) is one of the most malignant primary tumors in humans. Despite standard therapeutic strategy with tumor resection combined with radiochemotherapy, the prognosis remains disappointed. Recently, deubiquitinating enzymes (DUBs) has been reported as potential cancer therapy...