Activating AMPK to Restore Tight Junction Assembly in Intestinal Epithelium and to Attenuate Experimental Colitis by Metformin

• Main Authors: Lu Chen (Author), Jie Wang (Author), Qian You (Author), Shuai He (Author), Qianqian Meng (Author), Jian Gao (Author), Xudong Wu (Author), Yan Shen (Author), Yang Sun (Author), Xuefeng Wu (Author), Qiang Xu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Adenosine monophosphate-activated protein kinase (AMPK), a crucial molecule in energy metabolism, is reported to play a potential role in gut epithelial differentiation and barrier function recently; however, its performance and mechanisms in the pathological process of inflammatory bowel diseases r...