Neutrophil activation, acute lung injury and disease severity in Plasmodium knowlesi malaria.

• Main Authors: Angelica F Tan (Author), Sitti Saimah Binti Sakam (Author), Kim Piera (Author), Giri S Rajahram (Author), Timothy William (Author), Bridget E Barber (Author), Nicholas M Anstey (Author), Matthew J Grigg (Author), Steven Kho (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The risk of severe malaria from the zoonotic parasite Plasmodium knowlesi approximates that from P. falciparum. In severe falciparum malaria, neutrophil activation contributes to inflammatory pathogenesis, including acute lung injury (ALI). The role of neutrophil activation in the pathogenesis of se...