Activation of Glutathione Peroxidase 4 as a Novel Anti-inflammatory Strategy

• Glavni autori: Cong Li (Autor), Xiaobing Deng (Autor), Xiaowen Xie (Autor), Ying Liu (Autor), José Pedro Friedmann Angeli (Autor), Luhua Lai (Autor)
• Format: Knjiga
• Izdano: Frontiers Media S.A., 2018-10-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

The anti-oxidative enzyme, glutathione peroxidase 4 (GPX4), helps to promote inflammation resolution by eliminating oxidative species produced by the arachidonic acid (AA) metabolic network. Up-regulating its activity has been proposed as a promising strategy for inflammation intervention. In the pr...