Involvement of M1 Macrophage Polarization in Endosomal Toll-Like Receptors Activated Psoriatic Inflammation

• Main Authors: Chih-Hao Lu (Author), Chao-Yang Lai (Author), Da-Wei Yeh (Author), Yi-Ling Liu (Author), Yu-Wen Su (Author), Li-Chung Hsu (Author), Chung-Hsing Chang (Author), S.-L. Catherine Jin (Author), Tsung-Hsien Chuang (Author)
• Format: Book
• Published: Hindawi Limited, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Psoriasis is a chronic inflammatory skin disorder that affects ~2%-3% of the worldwide population. Inappropriate and excessive activation of endosomal Toll-like receptors 7, 8, and 9 (TLRs 7-9) at the psoriatic site has been shown to play a pathogenic role in the onset of psoriasis. Macrophage is a...