TNF-α stimulated exosome derived from fibroblast-like synoviocytes isolated from rheumatoid arthritis patients promotes HUVEC migration, invasion and angiogenesis by targeting the miR-200a-3p/KLF6/VEGFA axis

• Hauptverfasser: Bin Zhang (Verfasst von), Juanfang Gu (Verfasst von), Yiwen Wang (Verfasst von), Linfeng Guo (Verfasst von), Jiangzhen Xie (Verfasst von), Mingfeng Yang (Verfasst von)
• Format: Buch
• Veröffentlicht: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

AbstractThe pathogenesis of rheumatoid arthritis (RA) is heavily impacted by the inflammation and activation of fibroblast-like synoviocytes (FLS). The objective of this investigation is to clarify the involvement of exosomes derived from FLS stimulated by tumour necrosis factor α (TNF-α) in angioge...