Therapeutic vs. Suprapharmacological Metformin Concentrations: Different Effects on Energy Metabolism and Mitochondrial Function in Skeletal Muscle Cells in vitro

• मुख्य लेखकों: Kasja Pavlovic (लेखक), Nina Krako Jakovljevic (लेखक), Andjelka M. Isakovic (लेखक), Tijana Ivanovic (लेखक), Ivanka Markovic (लेखक), Nebojsa M. Lalic (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Metformin is an oral antidiabetic agent that has been widely used in clinical practice for over 60 years, and is currently the most prescribed antidiabetic drug worldwide. However, the molecular mechanisms of metformin action in different tissues are still not completely understood. Although metform...