The Cannabinoid-Like Compound, VSN16R, Acts on Large Conductance, Ca²⁺-Activated K⁺ Channels to Modulate Hippocampal CA1 Pyramidal Neuron Firing

• Main Authors: Setareh Tabatabaee (Author), David Baker (Author), David L. Selwood (Author), Benjamin J. Whalley (Author), Gary J. Stephens (Author)
• Format: Book
• Published: MDPI AG, 2019-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Large conductance, Ca²⁺-activated K⁺ (BK_Ca) channels are widely expressed in the central nervous system, where they regulate action potential duration, firing frequency and consequential neurotransmitter release. Moreover, drug act...